Vardanyan David Martinovich (Assistant State Educational Institution of Higher Professional Education of the Russian Scientific Research Medical University. Nikolay Ivanovich Pirogov Russian Ministry of Health)
Cherniakov Artyom Viktorovich (Candidate of Medical Sciences, Associate Professor State Educational Institution of Higher Professional Education of the Russian Scientific Research Medical University. Nikolay Ivanovich Pirogov Russian Ministry of Health)
Stupin Viktor Aleksandrovich (Doctor of Medical Sciences, Professor State Educational Institution of Higher Professional Education of the Russian Scientific Research Medical University. Nikolay Ivanovich Pirogov Russian Ministry of Health)
Grigoriev Aleksej Sergeevich (Assistant
State Educational Institution of Higher Professional Education of the Russian Scientific Research Medical University. Nikolay Ivanovich Pirogov Russian Ministry of Health
)
Balandina Anna Nikolaevna (Ph.D.
Graduate School of Molecular and Experimental Medicine Federal Research and Clinical Center of Pediatric Hematology, Oncology and Immunology. Dmitry Rogachev Russian Ministry of Health
)
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Treatment of patients with deep veins thrombosis is the first holding anticoagulant therapy, including assignment heparin and other anticoagulants. The most commonly used drug group is a vitamin K antagonist warfarin. Treatment of varfarin effectively controlled by the level of INR, where he was received by the target value range from 2 to 3. The aim is to determine the suitability of a new global method of hemostasis system evaluation (Thrombodynamics test) to assess the effectiveness varfarinoterapii in patients with thrombosis of deep veins.
In total, the study included 60 patients with verified thrombosis of the deep veins of the lower extremities.
The study warfarin in patients with thrombosis of deep veins significantly increases Tlag test indicator Trombodinamcs which at INR 2 has a high positive correlation with this option and can be used in assessing the effectiveness of varfarin. Statistically significant changes in Vi, Vs and d-dimer background was not observed.
Keywords:deep vein thrombosis, anticoagulation, coagulation tests, Thrombodynamics test.
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Citation link:
Vardanyan D. M., Cherniakov A. V., Stupin V. A., Grigoriev A. S., Balandina A. N. Monitoring the effectiveness of varfarin treatment in patients with deep vein thrombosis of the lower limbs in hospital // Современная наука: актуальные проблемы теории и практики. Серия: Естественные и Технические Науки. -2016. -№05. -С. 60-66 |
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