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The influence of photodynamic therapy on adhesive properties of erythrocytes and the activity of leukocytes in human blood cancer

Purckhvanidze Violleta Alexandrovna  (candidate of medical sciences, Chief shaman Medical Center "LazerVita")

Simakov Yuriy Georgievich  (Doctor of Biological teaching, professor, MGU technologies and control them. K.G.Razumovskogo )

Investigated the state of the cellular elements in the peripheral blood drop from the finger using optical complex and a computer program "VideoZavr" on micropreparations type "the crushed drop" obtained from 15 patients with cervical cancer, kidney cancer, vulvar cancer, breast cancer, and 8 subjects (control group) increased adhesion of red blood cells. The cancer patients underwent photodynamic therapy, and subjects in the control group were only injected photoditazine. After photodynamic therapy, there was a reduction of the adhesion of red blood cells in the peripheral blood, and in 20 minutes is the disintegration of sludge of red blood cells by about 80 %. The revealed changes of adhesion of erythrocytes after administration of fotoditazin photodynamic therapy and contribute to the amplification of tissue respiration and improving cellular immunity. Release of leukocytes, previously clamped aggregated red blood cells allows white blood cells to reach the gaps formed plasma to increase mobility and to proceed to enhanced phagocytosis. The process of strengthening the phagocytic activity of leukocytes was observed directly in the field of view of the microscope, on the vital drug blood taken 20 minutes after photodynamic therapy. Activation of cellular immunity occurs due to the increase of phagocytosis of leukocytes and increase the motility of white blood cells.

Keywords:photodynamic therapy, tumor cancer, photoditazine, adhesion of erythrocytes, the activity of leukocytes

 

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Citation link:
Purckhvanidze V. A., Simakov Y. G. The influence of photodynamic therapy on adhesive properties of erythrocytes and the activity of leukocytes in human blood cancer // Современная наука: актуальные проблемы теории и практики. Серия: Естественные и Технические Науки. -2016. -№05. -С. 82-87
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