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Personalized medicine in pain management

Golubenko Ekaterina Olegovna  (I.M. Sechenov First Moscow State Medical University of the Russian Ministry of Health (Sechenov University); Moscow )

Silina Ekaterina Vladimirovna  (I.M. Sechenov First Moscow State Medical University of the Russian Ministry of Health (Sechenov University); Moscow )

Orlova Alexandra Sergeevna  (I.M. Sechenov First Moscow State Medical University of the Russian Ministry of Health (Sechenov University); Moscow )

The effectiveness and specificity of modern analgesics are insufficient. Studies of genetic polymorphisms associated with pain syndromes and the metabolism of drugs foreshadow a new therapeutic approach with targeted analgesia and fewer side effects. The purpose of this work is to assess the association of the patient's genetic profile and its response to perception, the onset of pain and the therapeutic response to analgesics.

Keywords:pain syndrome, targeted analgesia, genetic profile, pain pharmacogenetics, opioid analgesics, antiepileptic drugs, cyclic antidepressants.

 

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Citation link:
Golubenko E. O., Silina E. V., Orlova A. S. Personalized medicine in pain management // Современная наука: актуальные проблемы теории и практики. Серия: Естественные и Технические Науки. -2017. -№07-08. -С. 107-112
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