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Glial tumors of the brain: brief review of literature

Sehweil SalahM.M.   (Candidate of Medical Sciences, The Rostov State Medical University Ministry of Health of the Russian Federation)

Glial tumors are the most common group of primary brain tumors in the adult population. Among the most aggressive of the gliomas are glioblastoma and anaplastic astrocytoma. The article reflects the main theories of the development of glial brain tumors and modern aspects of their treatment. Despite the generally accepted complex treatment of highly differentiated glial tumors, including surgical treatment, chemo - and radiotherapy, the prognosis of patients ' survival remains unfavorable. The average life expectancy of patients is about a year from the moment of diagnosis. The complexity of curation of patients with malignant glial tumors due to infiltrative growth of tumors, the development of resistance to most of the known treatments. The article analyzes the complications caused by chemo-and radiotherapy. Surgical treatment of malignant tumors often leads to a worsening of neurological deficits and permanent invalidization patients. The low efficiency of treatment of malignant tumors of the brain remains the most difficult, urgent and unresolved problem, which requires the study of pathogenetic mechanisms of their development and the search for new ways of treatment.

Keywords:glioblastoma, glioma, chemotherapy, immunotherapy, infiltrative growth.
 

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Citation link:
Sehweil S. Glial tumors of the brain: brief review of literature // Современная наука: актуальные проблемы теории и практики. Серия: Естественные и Технические Науки. -2018. -№05. -С. 191-195
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