Pateyuk Andrey Vladimirovich (doctor of medical sciences, professor, Transbaikal State University, Chita)
Maximenya Maria Vladimirovna (Candidate of Medical Sciences, Senior Researcher, Chita State Medical Academy, Chita)
Tereshkov Pavel Petrovich (Candidate of Medical Sciences, Chita State Medical Academy, Chita)
Zhilyaeva Marianna Sergeevna (Candidate of Psychological Sciences, Associate Professor, Transbaikal State University, Chita)
Kosyakova Elena Sergeevna (Resident, Chita State Medical Academy, Chita)
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In the blood serum of women suffering from osteopenia and osteoporosis (during menopause), concentrations of free thyroxin (T4) were determined by ELISA, free triiodothyronine (T3), cortisol, parathyroid hormone (PTH), the precursor of calcitriol (25-OH vitamin D) and estrater eteromer (PTH); - by the method of chemiluminescent immunoassay. A decrease in estradiol and an increase in the amount of parathyroid hormone, as well as an increase in the metabolite of vitamin D (25 (OH) D), were found. In addition, estradiol / PTH values decrease in this category of persons. Using multivariate analysis, it was established that the most significant factors for the formation of osteopenia and osteoporosis in women are the quantities of parathyroid hormone, 25-OH vitamin D, estradiol, and the value of the indicator estradiol / PTH.
Keywords:Osteoporosis, medico-social problem, hormones, women.
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Citation link:
Pateyuk A. V., Maximenya M. V., Tereshkov P. P., Zhilyaeva M. S., Kosyakova E. S. Osteoporosis, as a medico-social problem. Informative assessment of the hormonal spectrum for the early diagnosis of osteoporosis in women // Современная наука: актуальные проблемы теории и практики. Серия: Естественные и Технические Науки. -2019. -№06. -С. 178-182 |
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