Gubar Tatiana K. (Obstetrician-gynecologist, a graduate student, Banzarov Buryat State University, Ulan–Ude, Russia)
Alekseeva Lilia L. (MD, Associate Professor, Banzarov Buryat State University; deputy chief doctor of the medical work at the State Autonomous Healthcare Institution "Republican Perinatal Center", Ulan–Ude, the Republic of Buryatia, Russia)
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One of the causes of bleeding in the second half of pregnancy is placenta previa. The frequency of this complication is from 0.2 to 1.5%. Over the past decade, there has been a growth trend. A direct relationship between the frequency of placenta previa and hereditary defects in the hemostatic system has been proved. For example, reduced PAI - 1 synthesis causes desynchronization of the processes of fibrinolysis and fibrin formation, thrombotic mechanisms are enhanced, which leads to implantation defects and a decrease in the depth of decidual trophoblast invasion.
Keywords:placenta previa, bleeding, pregnancy, hemostasis
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Citation link:
Gubar T. K., Alekseeva L. L. Successful pregnancy outcome in a patient with complete placenta previa in case of genetically determined thrombophilia // Современная наука: актуальные проблемы теории и практики. Серия: Естественные и Технические Науки. -2019. -№12. -С. 124-126 |
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