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Features of pathogenesis and pharmacological therapy of patients with diabetic encephalopathy

Popova Ksenia Alexandrovna  (FSBEI of HE "National Research Mordovian State University named after N.P. Ogareva ", Saransk)

Ryzhov Artem Vladimirovich  (FSBEI of HE "National Research Mordovian State University named after N.P. Ogareva ", Saransk)

Danilova Yana Andreevna  (FSBEI of HE "National Research Mordovian State University named after N.P. Ogareva ", Saransk)

Malynina Angelina Vladimirovna  (FSBEI of HE "National Research Mordovian State University named after N.P. Ogareva ", Saransk)

Sychev Ivan Vitalevich  (graduate student, FSBEI of HE "National Research Mordovian State University named after N.P. Ogareva ", Saransk)

Prokopova Natalya Nikolaevna  (general practitioner, FSBEI of HE "National Research Mordovian State University named after N.P. Ogareva ", Saransk)

Belova Ludmila Alexandrovna  (Candidate of Medical Sciences, Associate Professor, FSBEI of HE "National Research Mordovian State University named after N.P. Ogareva ", Saransk)

Shuligina Irina Vasilevna  (Candidate of Medical Sciences, Associate Professor, FSBEI of HE "National Research Mordovian State University named after N.P. Ogareva ", Saransk)

This article addresses the issues of epidemiology, pathogenesis, and clinical manifestations of such a frequent complication of diabetes as diabetic encephalopathy. The question of the need for early diagnosis of diabetic encephalopathy is discussed, since its later detection leads to social maladaptation and disability of patients. Several mechanisms of the formation of this complication are considered, among which special attention is paid to the theory of oxidative stress. Particular attention is paid to the pathogenesis substantiation of adequate medical correction of clinical manifestations by such groups of drugs as antioxidants, drugs that improve cerebral circulation, nootropics, neuroprotectors, neurotransmitters, peptides. The question of the need to create uniform algorithms for the provision of specialized medical care to patients with diabetic encephalopathy is discussed.

Keywords:diabetes mellitus, diabetic encephalopathy, cognitive impairment, oxidative stress, antioxidants.

 

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Citation link:
Popova K. A., Ryzhov A. V., Danilova Y. A., Malynina A. V., Sychev I. V., Prokopova N. N., Belova L. A., Shuligina I. V. Features of pathogenesis and pharmacological therapy of patients with diabetic encephalopathy // Современная наука: актуальные проблемы теории и практики. Серия: Естественные и Технические Науки. -2020. -№05. -С. 207-212 DOI 10.37882/2223–2966.2020.05.36
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