Журнал «Современная Наука»

Russian (CIS)English (United Kingdom)
 MOSCOW +7(495)-142-86-81

Activation of cholinergic system of soil nematode caenorhabditis elegans maupas by Allium sativum l. juice

Egorova A.   (Research Institute for Problems of Ecology and Mineral Wealth Use of Tatarstan Academy of Sciences, Kazan)

Kolsanova R.   (Research Institute for Problems of Ecology and Mineral Wealth Use of Tatarstan Academy of Sciences, Kazan)

Kalinnikova T.   (Research Institute for Problems of Ecology and Mineral Wealth Use of Tatarstan Academy of Sciences, Kazan)

In experiments with soil nematode C. elegans it was shown that Allium sativum juice is toxic for nematodes. The target of toxic action of A. sativum is C. elegans nervous system. A. sativum juice increased the sensitivity of C. elegans organism to negative action of levamisole, agonist of nicotinic acetylcholine receptors. A. sativum juice also increased the nematodes sensitivity to the rise in endogenic acetylcholine level by partial inhibition of acetylcholine esterase by aldicarb. The results of this work show that the mechanism of toxic action of A. sativum juice consists in activation of nematodes’ cholinergic system.

Keywords:Allium sativum, anthelmintic drugs, Caenorhabditis elegans, levamisole, nicotinic acetylcholine receptors.
 

Read the full article …

Citation link:
Egorova A. , Kolsanova R. , Kalinnikova T. Activation of cholinergic system of soil nematode caenorhabditis elegans maupas by Allium sativum l. juice // Современная наука: актуальные проблемы теории и практики. Серия: Естественные и Технические Науки. -2020. -№06. -С. 17-22 DOI DOI 10.37882/2223-2966.2020.06.10
LEGAL INFORMATION:
Reproduction of materials is permitted only for non-commercial purposes with reference to the original publication. Protected by the laws of the Russian Federation. Any violations of the law are prosecuted.
© ООО "Научные технологии"

Terms Publications

Issues of the journals (Archive)

ECONOMICS AND LAW
HUMANITIES
NATURAL AND TECHNICAL SCIENCES
COGNITION

Серия - Natural and Technical Sciences