Borovkova Е. А. (Stavropol State Medical University)
Alieva Е. V. (MD, PhD, DSc, Stavropol State Medical University)
Kovalyov D. A. (PhD, Stavropol Anti-Plague Institute)
Shapakov N. v (research fellow, Stavropol Anti-Plague Institute)
Karaseva А. B. (research fellow, Institute of Experimental Medicine (St. Petersburg))
Tsapieva А. N. (research fellow, Institute of Experimental Medicine (St. Petersburg))
Suvorov A. N. (MD, PhD, DSc, Institute of Experimental Medicine (St. Petersburg))
Guo D. (Institute of Agro-Food Science and Technology, Shandong Academy of Agricultural Sciences, Jinan, China)
Yang J. (Institute of Agro-Food Science and Technology, Shandong Academy of Agricultural Sciences, Jinan, China)
Zhao S. (Institute of Agro-Food Science and Technology, Shandong Academy of Agricultural Sciences, Jinan, China)
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Identification, determination of phenotypic antibiotic resistance, genome annotation and the search for antibiotic resistance genes were performed to address the issue of the safe use of three strains of indigenous intestinal lactobacilli as autoprobiotics. As a result of the study the strains were identified as Lactobacillus paracasei 347-16, Lactobacillus plantarum 123-17 and Lactobacillus plantarum 83-18, had typical for lactobacilli phenotypic antibiotic resistance profile, different number of plasmids and a similar set of antibiotic resistance genes located on chromosome.
Keywords:autoprobiotics, lactobacilli, antibiotic resistance, antibiotic resistance genes.
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Citation link:
Borovkova Е. А., Alieva Е. V., Kovalyov D. A., Shapakov N. v., Karaseva А. B., Tsapieva А. N., Suvorov A. N., Guo D. , Yang J. , Zhao S. Safety assessment of perspective as autoprobiotics indigenic intestinal lactobacilli // Современная наука: актуальные проблемы теории и практики. Серия: Естественные и Технические Науки. -2020. -№07. -С. 14-19 DOI 10.37882/2223-2966.2020.07.05 |
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