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Proliferative activity of dermal fibroblasts depending on the concentration of carbon dots

Golderova Aitalina Semenovna  (Doctor of Medical Sciences, Professor, North-Eastern Federal University named after M.K. Ammosov)

Shadrina Svetlana Semyonovna  (Senior Researcher, North-Eastern Federal University named after M.K. Ammosov)

Nikolaeva Irina Eduardovna  (Researcher, North-Eastern Federal University named after M.K. Ammosov)

Egorova Marfa Nikitichna  (Researcher, North-Eastern Federal University named after M.K. Ammosov)

Evseeva Yulia Ruslanovna  (laboratory assistant, North-Eastern Federal University named after M.K. Ammosov)

Troev Ivan Petrovich  (Researcher, North-Eastern Federal University named after V.I. M.K. Ammosov)

Егоров Андрей Николаевич  (Лаборант, Северо-Восточный Федеральный Университет им. М.К. Аммосова, г. Якутск)

The article describes an experimental study on human dermal fibroblast cells. The aim of the study was to evaluate in vitro the proliferative activity of human dermal fibroblasts depending on the concentration of carbon dots (CD). By the end of the experiment, the most "affected" was the group to which the largest volume of carbon dots solution (50 ml) was added, the group with the smallest volume (10 ml) was practically not "affected". The results obtained confirm that the toxicity of UT depends on the protocol of their manufacture and is detected only at higher concentrations.

Keywords:carbon dots, fibroblasts, cytotoxicity, cell culture, proliferation, hydrothermal method, bird cherry, positive charge, concentration, in vitro.

 

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Citation link:
Golderova A. S., Shadrina S. S., Nikolaeva I. E., Egorova M. N., Evseeva Y. R., Troev I. P., Егоров А. Н. Proliferative activity of dermal fibroblasts depending on the concentration of carbon dots // Современная наука: актуальные проблемы теории и практики. Серия: Естественные и Технические Науки. -2021. -№06. -С. 18-25 DOI 10.37882/2223-2966.2021.06.10
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