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Introduction. In recent years, there has been an increased interest of researchers in the problems of the development of metabolic syndrome (MS) in menopausal women, due to the high risk of developing cardiovascular complications and type 2 diabetes mellitus. There are the following factors that contribute to the development of MS: genetic predisposition, sedentary lifestyle, low socio-economic status, peculiarities of eating behavior. Despite a fairly broad discussion of the development of MS, the issues of pathogenesis and conditions that contribute to the formation of MS continue to be discussed.
The aim of the study is to identify somatic and gynecological pathology that forms risk factors for the development of menopausal metabolic syndrome in women.
Methods: To achieve this goal, we examined 184 women aged 54.2 (0.5) years who were in menopause before 5 years. Of these, 87 were diagnosed with menopausal metabolic syndrome – they made up the main group. The comparison group consisted of 97 menopausal women without metabolic syndrome. The groups were comparable in terms of social status, level of education and nature of work activity.
Results and discussion. Risk factors for the development of menopausal metabolic syndrome were identified. It was found that of the gynecological diseases suffered, the most significant were SPMN and endometrial polyps. Of the somatic diseases suffered, the most important were diseases of the nervous system, in particular astheno-vegetative syndrome, hypertension, pathology of the cardiovascular system. Obesity was less significant than the listed conditions.
Conclusion. Obesity, although it is one of the manifest forms of manifestation of the syndrome, does not play a leading role in the formation of pathology of the cardiovascular system or the development of type 2 diabetes, as the most threatening complications and extreme forms of MS. Menopausal symptoms, often accompanying menopause, should also be differentiated from the clinical manifestations of MS and those diseases that accompany or complicate the existing pathology during this period of a woman's life.
Keywords:menopausal metabolic syndrome, risk factors, obesity, menopausal syndrome.
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