Sultanova Oksana Esedullayevna (Assistant, Federal State Budgetary Educational Institution of Higher Education "Astrakhan State Medical University" of the Ministry of Health of the Russian Federation)
Chernysheva Elena Nikolaevna (Associate Professor, Doctor of Medical Sciences
Federal State Budgetary Educational Institution of Higher Education "Astrakhan State Medical University" of the Ministry of Health of the Russian Federation)
Kuzmichev Bogdan Yurievich (Candidate of Medical Sciences,
Federal State Budgetary Educational Institution of Higher Education "Astrakhan State Medical University" of the Ministry of Health of the Russian Federation, Assistant of the Department of Clinical Immunology with a postgraduate course)
Popov Evgeny Antonovich (Professor, projector for educational work, Head of the Department of Polyclinic and Emergency Medicine
Doctor of Medical Sciences Professor
Federal State Budgetary Educational Institution of Higher Education "Astrakhan State Medical University" of the Ministry of Health of the Russian Federation)
Osipova Anastasia Alexandrovna (Federal State Budgetary Educational Institution of Higher Education "Astrakhan State Medical University" of the Ministry of Health of the Russian Federation doctor of Department No. 1 of the State Medical Institution No. 3 named after S.M.Kirov)
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A special place among diseases of the cardiovascular system is occupied by acute coronary syndrome, which has a tendency to rejuvenate in the last 10 years. In more than 40% of cases, acute coronary syndrome is combined with connective tissue dysplasia syndrome. The purpose of this study is to study and analyze the relationship between homocysteine levels and lipid profile parameters in patients with acute coronary syndrome against the background of undifferentiated connective tissue dysplasia syndrome.
In the group of patients both with acute coronary syndrome (ACS) without the syndrome of undifferentiated connective tissue dysplasia (UCTD) and with ACS + UCTD, statistically significant changes in the levels of homocysteine, total cholesterol (TC), low-density lipoprotein (LDL), high-density lipoproteins (HDL) and atherogenic index compared with the control group, while in the group of patients with comorbidity, changes in the levels of Hcy, total cholesterol, LDL and atherogenic index were statistically significantly higher compared to the group of patients with ACS without UCTD, and the level of HDL was statistically significantly lower.
Also, the presence of statistically significant relationships between the levels of Hcy, total cholesterol, LDL, HDL and the atherogenic index was revealed, which indirectly indicates that a change in the level of one of them affects the change in the level of the other, or that there is a common reason for increasing the levels of Hcy, total cholesterol , LDL and atherogenic index and a decrease in HDL levels in the group of patients with both ACS without UCTD, and a more pronounced degree in the group of patients with ACS + UCTD.
Keywords: dysplasia, acute coronary syndrome, lipid profile, homocysteine
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Citation link:
Sultanova O. E., Chernysheva E. N., Kuzmichev B. Y., Popov E. A., Osipova A. A. The relationship between homocysteine levels and lipid profile indicators in patients with acute coronary syndrome against the background of undifferentiated connective tissue dysplasia syndrome // Современная наука: актуальные проблемы теории и практики. Серия: Естественные и Технические Науки. -2022. -№10. -С. 219-223 DOI 10.37882/2223-2966.2022.10.31 |
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