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The effectiveness of statin therapy for patients with high cardiovascular risk. The use of statins in clinical practice: concomitant diseases and complications

Akhmedov Azedin Eshrefovich  (cardiologist, assistant of the Department of Faculty Therapy of Dagestan State Medical University, Makhachkala)

Garunov Zalimkhan Omarievich  (cardiologist, assistant of the Department of Faculty Therapy of Dagestan State Medical University, Makhachkala)

Khizriev Magomedkamil Davutovich  (cardiologist, assistant of the Department of Faculty Therapy of Dagestan State Medical University, Makhachkala)

Magadova Galina Magadovna  (cardiologist, assistant of the Department of Faculty Therapy of Dagestan State Medical University, Makhachkala)

Statins ( GMC-CoA reductase inhibitors) are the first-line drugs for the treatment of dyslipidemia , which have been used in cardiology since the end of the 20th century and during this time have managed to prolong the lives of many millions of patients . This article reveals the relevance of the use of statin therapy in order to reduce the level of low -density lipoprotein cholesterol and reduce the risk of developing cardiovascular diseases . This type of treatment is indeed very effective and contributes to a drop in the level of “ bad ” cholesterol , which helps to reduce the risk of developing CVD and possible complications .The use of statins for 5-6 years helps to reduce probability of developing myocardial infarction by 30-45% and sudden cardiac death , and also reduces the risk of ischemic stroke be 25-30%. As a rule , taking statins in the absence of serious side effects lasts for life .

Keywords:Statins , statin therapy , atherosclerosis , atherosclerotic plaque , LDL-cholesterol, atorvastatin , ACS .

 

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Citation link:
Akhmedov A. E., Garunov Z. O., Khizriev M. D., Magadova G. M. The effectiveness of statin therapy for patients with high cardiovascular risk. The use of statins in clinical practice: concomitant diseases and complications // Современная наука: актуальные проблемы теории и практики. Серия: Естественные и Технические Науки. -2022. -№12/2. -С. 222-225 DOI 10.37882/2223-2966.2022.12-2.06
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