Lobanov Yuri Sergeevich (Candidate of Medical Sciences, Associate Professor of the Department of Faculty Surgery with the course of Urology "Chita State Medical Academy")
Shapovalov Konstantin Gennadievich (Doctor of Medical Sciences, Professor, Head of the Department of Anesthesiology and Resuscitation "Chita State Medical Academy")
Lobanov Sergey Leonidovich (MD, Professor, Head of the Department of Faculty Surgery with the course of Urology "Chita State Medical Academy")
Lobanov Leonid Sergeevich (Candidate of Medical Sciences, Deputy.Chief Surgeon of the City Clinical Hospital No. 1)
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Retroperitoneal access with minimally invasive interventions in the retroperitoneal space has been actively developing in recent years. This requires the creation and maintenance of a retro-pneumoperitoneum with the inevitable compression of surrounding tissues and cavities. The pathophysiological reactions that occur in this case require study. A special place is occupied by the possible risk of thromboembolic complications.
The purpose of the study: To study the effect of retroperitoneal space compression on individual hemostasis links.
Material and methods: Studies were conducted in 48 patients operated on for kidney cysts using retroperitoneal access with various compression modes. Spontaneous and induced platelet aggregation, as well as the level, rate and degree of aggregation were studied. Along with this, the parameters of coagulograms before and after surgery were studied.
Results and conclusion: Compression above 12 mm Hg. Art. revealed an increase in spontaneous platelet aggregation by 18%, an increase in the level of induced aggregation by 11% (0.044322), while the degree of aggregation of induced aggregation increased by 14% (p = 0.012564). Under the influence of the selected retropneumoperitoneum regimen, a reduction in the time of induced aggregation by 10% (p=0.012564) was observed, in turn, the rate of induced aggregation was increased by 13% (p=0.004821).
The obtained changes in the aggregation properties of platelets demonstrate an increase in their activity in response to the creation of artificial cavities that maintain pressure due to the injected gas in the retroperitoneal space above 12 mm Hg. Art. At pressures below 12 mm Hg. Art. no changes in vascular-platelet hemostasis were detected.
Keywords:retropneumoneritoneum, hemostasis, platelet aggregation, compression
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Citation link:
Lobanov Y. S., Shapovalov K. G., Lobanov S. L., Lobanov L. S. REACTIONS OF VASCULAR-PLATELET HEMOSTASIS IN CONDITIONS OF HYPERTENSION IN THE RETROPERITONEAL SPACE DURING SURGICAL OPERATIONS // Современная наука: актуальные проблемы теории и практики. Серия: Естественные и Технические Науки. -2023. -№01. -С. 200-204 DOI 10.37882/2223–2966.2023.01.24 |
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