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BIOMARKER ANALYSIS IN WOMEN WITH "SMALL FORMS" OF EXTERNAL ENDOMETRIOSIS

Tselkovich Lyudmila   (Doctor of Medical Sciences Professor of the Department of Ultrasound Diagnostics, IPO SamSMU Samara State Medical University Russia, Samara )

Balter Regina   (Candidate of Medical Sciences, Professor Head of the Department of Ultrasound Diagnostics, IPO SamSMU Samara State Medical University Russia, Samara )

Ibragimova Alina   (Candidate of Medical Sciences Associate Professor of the Department of Ultrasound Diagnostics, IPO SamSMU Samara State Medical University Russia, Samara )

Ivanova Tatiana   (Candidate of Medical Sciences Associate Professor, Department of Ultrasound Diagnostics, IPO SamSMU Samara State Medical University Russia, Samara )

Blazhnova Elena   (Applicant for the Department of Ultrasound Diagnostics, IPO SamSMU Samara State Medical University Russia, Samara )

Ohanisyan Anna   (Applicant for the Department of Ultrasound Diagnostics, IPO SamSMU Samara State Medical University Russia, Samara )

The informativeness of pro-inflammatory cytokines 1β (IL-1β), interleukin 6 (IL-6) and tumor markers CA-125, HE-4, ROMA index in the dynamics of the menstrual cycle in women with stages I-II (according to rAFS) of external endometriosis was evaluated. The results of examinations of 208 patients were processed in accordance with medical statistics. It has been established that in the presence of clinical symptoms and dubious sonographic markers of external endometriosis, on days 3–5 and 21–23 of the menstrual cycle, an examination for biochemical markers IL-1β and IL-6 is necessary, since their increase allows differentiating the presence of pathology.

Keywords:endometriosis, biomarkers, interleukin-1β, interleukin-6, CA-125, HE-4, ROMA index

 

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Citation link:
Tselkovich L. , Balter R. , Ibragimova A. , Ivanova T. , Blazhnova E. , Ohanisyan A. BIOMARKER ANALYSIS IN WOMEN WITH "SMALL FORMS" OF EXTERNAL ENDOMETRIOSIS // Современная наука: актуальные проблемы теории и практики. Серия: Естественные и Технические Науки. -2023. -№01. -С. 246-249 DOI 10.37882/2223–2966.2023.01.37
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