Alipov Vladimir Vladimirovich (Head of the Department of Operative Surgery and Topographic Anatomy, Academician of the Russian Academy of Medical Sciences, Doctor of Medical Sciences, Professor, Saratov State Medical University named after V.I. Razumovsky)
Kapralov Sergey Vladimirovich (Head of the Department of Faculty Surgery and Oncology, Doctor of Medical Sciences, Professor, Saratov State Medical University named after V.I. Razumovsky)
Rychlov Andrey Sergeyevich (Director of Educational Scientific and Technological Center «Veterinary Hospital» Saratov State Agrarian University named after N.I. Vavilov)
Musaelyan Ara Gagikovich (Assistant of the department of operative surgery and topographic anatomy, Saratov State Medical University named after V.I. Razumovsky)
Polidanov Maksim Andreevich (6th year student of medical faculty, Saratov State Medical University named after V.I. Razumovsky)
Kondrashkin Ivan Evgenievich (6th year student of medical faculty, Saratov State Medical University named after V.I. Razumovsky)
Takhmezov Alik Eldarovich (6th year student of the faculty of pediatrics, Saratov State Medical University named after V.I. Razumovsky )
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Objective. to substantiate experimentally a method of modeling of local isolated peritonitis. Materials and methods. The local isolated peritonitis was modeled in the experiments on 40 white laboratory rats weighing 190 ± 20 g. The modeling consisted in infecting of the distal balloon of the modified two-channel catheter with 15% fecal suspension taken from the blind intestine in sodium chloride isotonic solution. The catheter was tied at the base and the balloon was left inflated for 6 days after which we evaluated the integral index of the general state of the animal, its planimetric parameters, the microbiological picture of the abscess cavity content and performed ultrasound and morphological studies of the formed local delimited peritonitis. Results. As a result of the performed research, specific features and classical clinical signs of the formed local isolated peritonitis were determined and it was found out that the used non-invasive instrumental (ultrasound investigation and roentgenography) investigation methods are the effective ways of planimetric estimation of the modeled local isolated peritonitis. Conclusion. As a result, by the 6th day of the experiment, it has been proved that in the iliac area a circular cavity 2 cm3 in diameter with distinct walls and loops of the intestine soldered to them has been formed, i.e. the model of the classical local isolated peritonitis has been obtained.
Keywords:local limited peritonitis (LIP), modeling, experiment
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Citation link:
Alipov V. V., Kapralov S. V., Rychlov A. S., Musaelyan A. G., Polidanov M. A., Kondrashkin I. E., Takhmezov A. E. EXPERIMENTAL VALIDATION OF THE METHOD OF MODELING LOCAL ISOLATED PERITONITIS // Современная наука: актуальные проблемы теории и практики. Серия: Естественные и Технические Науки. -2023. -№03. -С. 142-145 DOI 10.37882/2223–2966.2023.03.02 |
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