Gorelova V. G. (Candidate of Medical Sciences, Associate
Professor of the Department of Pathology
Physiology FSBEI HE DSMU
Ministry of Health of Russia
)
Osmanova A. A. (Candidate of Medical Sciences, Associate
Professor of the Department of Pathology
Physiology FSBEI HE DSMU
Ministry of Health of Russia
)
Gazieva M. M. (4th year student of pediatric
Faculty of FSBEI HE DSMU
Ministry of Health of Russia
)
Yunusova Z. Z. (4th year student of medical and prophylactic
Faculty of FSBEI HE DSMU
Ministry of Health of Russia
)
Atalalieva P. G. (4th year student of medical and prophylactic
Faculty of FSBEI HE DSMU
Ministry of Health of Russia
)
Zeynalova G. I. (4th year student of medical and prophylactic
Faculty of FSBEI HE DSMU
Ministry of Health of Russia
)
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study of the activity of thyroperoxidase and cytochemical parameters of blood neutrophils in autoimmune thyroiditis (AIT) and the establishment of their possible relationships depending on the severity of the process. Material for histochemical studies were pieces of thyroid tissue taken from 27 patients with AIT after its subtotal resection. For cytochemical studies, we used venous blood taken from the same patients at admission, as well as on the 2nd and 5th days after the operation. The control was venous blood of 10 healthy volunteers aged 20-45 years.
The epithelial parenchyma of the gland in hypothyroidism is gradually replaced by lymphoid infiltrates. The activity of thyroperoxidase in AIT in the phase of hypothyroidism is low and is directly dependent on the severity of the pathological process. Cytochemical parameters of neutrophils in patients with AIT with hypothyroidism syndrome are significantly increased, which is especially pronounced in the last phase of the disease.
Keywords:autoimmune thyroiditis, thyroperoxidase, neutrophils, cationic proteins
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Citation link:
Gorelova V. G., Osmanova A. A., Gazieva M. M., Yunusova Z. Z., Atalalieva P. G., Zeynalova G. I. SOME CYTOCHEMICAL PARAMETERS OF BLOOD NEUTROPHILS IN AUTOIMMUNE THYROIDITIS AND THYROPEROXIDASE ACTIVITY // Современная наука: актуальные проблемы теории и практики. Серия: Естественные и Технические Науки. -2023. -№04. -С. 163-170 DOI 10.37882/2223–2966.2023.04.04 |
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