Chizhikov Andrey Valeryevich (PhD, thoracic surgeon,
Republican Clinical Oncology Centre,
Ufa, Russia
)
Abdullin Zamir Salikhovich (MD, thoracic oncologist,
Republican Clinical Oncology Centre,
Ufa, Russia
)
Yakovleva Olesya Gennadyevna (therapeutist,
Republican Clinical Oncology Centre,
Ufa, Russia
)
Sharipov Ural Firdausovich (anesthesiologist,
Republican Clinical Oncology Centre,
Ufa, Russia
)
Mukhtarov Ilmir Vinerovich (clinical resident
Republican Clinical Oncology Centre,
Ufa, Russia
)
Abdullin Ilmir Salikhovich (clinical resident
Republican Clinical Oncology Centre,
Ufa, Russia
)
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Purpose of the study: The main purpose of this study was to investigate the effect of short-term respiratory reserve therapy in patients with impaired respiratory function who are about to undergo surgical treatment for lung cancer.
Materials and Methods: The study included 18 patients diagnosed with moderate COPD in remission from 50 to 72 years old (17 men and 1 woman aged 60 years). The diagnosis was morphologically verified as non-small cell lung cancer (NSCLC). Patients were selected to be functionally inoperable, despite a high risk of postoperative complications due to the development of respiratory failure, but suitable for surgical lung resection, based on the stage of the disease. Patients were offered a 2-week course of preoperative rehabilitation: walking more than 1 km per day, breathing exercises and inhalation therapy. Spirometry data: FEV1 (forced expiratory volume in 1 second), FVC (functional vital capacity), six-minute walking distance, maximum inspiratory and expiratory volumes. Preoperative and postoperative spirometry was assessed.
Results: After preoperative pulmonary rehabilitation, there was a marked improvement in spirometry, air conduction (p<0.001), maximum inspiratory volume (12 cm H2O, p<0.001), 6-minute walk distance (53 m, p<0.001), forced vital lung capacity (p<0.001), predicted forced expiratory volume in 1 second (%) (p=0.001), forced expiratory volume in one second = 150 ml, p = 0.001, Δ maximum forced expiratory volume in one second: 650 ml ) and predicted maximum oxygen uptake (p<0.001). At the end of the rehabilitation course, 61% of patients (n = 11) evaluated by surgeons could be operated on.
Thus, it is advisable to send patients to rehabilitation before surgery before making a decision about the inoperability of the patient.
Keywords:lung cancer, COPD, respiratory function, preoperative rehabilitation course of treatment
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Citation link:
Chizhikov A. V., Abdullin Z. S., Yakovleva O. G., Sharipov U. F., Mukhtarov I. V., Abdullin I. S. RESTORATION OF THE RESPIRATORY RESERVE OF THE LUNGS IN PATIENTS BEFORE SURGERY // Современная наука: актуальные проблемы теории и практики. Серия: Естественные и Технические Науки. -2023. -№07/2. -С. 239-244 DOI 10.37882/2223-2966.2023.7-2.36 |
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