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CLINICAL CASE OF PARANEOPLASTIC NEUROLOGICAL SYNDROME IN BREAST CANCER

Tkach Vladislav Vladislavovich  (Cand.Med.Sci., Associate Professor of the Department of Nervous Diseases and Neurosurgery of the Order of the Red Banner of Labor Medical Institute named after. S.I. Georgievsky (Simferopol) )

Omelchenko Alexandra Dmitrievna  (Order of the Red Banner of Labor Medical Institute named after. S.I. Georgievsky (Simferopol) )

Chizhevskaya Daria Denisovna  (Order of the Red Banner of Labor Medical Institute named after. S.I. Georgievsky (Simferopol) )

Tkach Anton Vladislavovich  (Order of the Red Banner of Labor Medical Institute named after. S.I. Georgievsky (Simferopol) )

The article presents a clinical observation of a patient with a history of breast cancer and subacute development of paraneoplastic cerebellar degeneration (Anti-Yo-1). The anamnesis, clinical manifestations, and results of instrumental and laboratory research methods are described, which make it possible to establish a diagnosis of paraneoplastic neurological syndrome. The patient's management tactics using combined pulse therapy with high doses of glucocorticoid hormones (methylprednisolone) in combination with cyclophosphamide are presented. This patient belongs to a high-risk group for cancer pathology and requires further observation and in-depth diagnostic screening for the presence of malignant tumors.

Keywords:paraneoplastic syndrome, cerebellar degeneration, breast cancer, onconeural antibodies Anti-Yo-1, clinical case

 

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Citation link:
Tkach V. V., Omelchenko A. D., Chizhevskaya D. D., Tkach A. V. CLINICAL CASE OF PARANEOPLASTIC NEUROLOGICAL SYNDROME IN BREAST CANCER // Современная наука: актуальные проблемы теории и практики. Серия: Естественные и Технические Науки. -2024. -№01/2. -С. 101-102 DOI 10.37882/2223-2966.2024.1-2.14
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