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GUT MICROBIOLOGIC PROFILE IN PERSONS WITH PSYCHIATRIC DISORDERS

Bugero Nina Vladimirovna  (Doctor of Biological Sciences, Professor of the Department of Fundamental Medicine and Biochemistry "Pskov State University" )

Ilyina Natalia Anatolyevna  (Doctor of Biological Sciences, Professor "Pskov State University" )

Klinkovsky Alexander Igorevich  (Postgraduate student of the Department of Fundamental Medicine and General Pathology Pskov State University )

В Pskov State Budgetary Institution "Pskov Regional Clinical Center of Psychiatry and Narcology" examined 54 patients with various forms of mental disorders. General clinical and laboratory examination (analysis for dysbiotic disorders of intestinal flora and fecal analysis) was performed in all individuals. Determination of the composition of mutually beneficial existence of intestinal microflora representatives was carried out with the study of such parameters as the index of contagiousness, indicators of floristic significance, index of taxa constancy. In the examined persons against the background of decreasing normoflora constancy indexes included conditionally pathogenic microorganisms: p. Enterococcus (C=57,6 %) and fungi p. Candida (C=55.5 %). It was revealed that in patients with psychiatric disorders the number of dominant and floristically significant representatives of symbiotic microflora decreases with an increase in the number of representatives of transit microorganisms, this contributes to changes in the structure of the intestinal cenotype, as a result of the change of dominant species and the distribution of representatives of opportunistic microflora.

Keywords:contagiousness index, floristic significance, compositional constancy index, mental disorders, dominant species, enterococci, Candida fungi
 

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Citation link:
Bugero N. V., Ilyina N. A., Klinkovsky A. I. GUT MICROBIOLOGIC PROFILE IN PERSONS WITH PSYCHIATRIC DISORDERS // Современная наука: актуальные проблемы теории и практики. Серия: Естественные и Технические Науки. -2024. -№01. -С. 6-11 DOI 10.37882/2223-2966.2024.01.09
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