Tokaev Timur Kazbekovich (Researcher at the Department of Surgery for Tuberculosis of the Respiratory Organs of the NMIC of Phthisiopulmonology and Infectious Diseases of the Ministry of Health of the Russian Federation, thoracic surgeon, State Budgetary Healthcare Institution "Moscow Scientific and Practical Center for Tuberculosis Control of the Department of Health of the City of Moscow")
Shtykhno Anna Olegovna (ultrasound diagnostics doctor,
State Budgetary Healthcare Institution "Moscow Scientific and Practical Center for Tuberculosis Control of the Moscow City Health Department"
)
Bikbaev Alexander Sergeevich (Thoracic Surgeon, National Medical Research Center for Phthisiopulmonology and Infectious Diseases of the Ministry of Health of the Russian Federation)
Tokaev Valery Kazbekovich (Candidate of Medical Sciences, Oncologist, P.A. Herzen Moscow Scientific Research Institute)
Sinitsyn Mikhail Valeryevich (Doctor of Medical Sciences, Associate Professor, Deputy Chief Physician for Surgery, National Medical Research Center for Phthisiopulmonology and Infectious Diseases of the Ministry of Health of the Russian Federation, Professor of the Department of Phthisiology, N. I. Pirogov Russian National Research Medical University )
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The article provides information on the use of silver nanoparticles in the treatment of tuberculosis. Materials and methods. Silver nanoparticles of a certain size and concentration were used for the study. The effectiveness of the antimicrobial action of nanoparticles was evaluated in in vitro and in vivo models of tuberculosis infection. The research methods included the analysis of the effects of nanoparticles on pathogens, the study of their effect on the development of infection and the evaluation of treatment results. Results. The study showed that the use of silver nanoparticles in the treatment of tuberculosis is highly effective in inhibiting the growth of Mycobacterium tuberculosis, which causes tuberculosis. Silver nanoparticles have a strong antimicrobial effect and are able to effectively destroy pathogens, including those that show resistance to standard antibiotics. Conclusions. The use of silver nanoparticles represents a promising approach in the treatment of tuberculosis and other infections. Their powerful antimicrobial action and low toxicity make them an attractive option for use in clinical practice. Further research may provide a deeper understanding of the mechanisms of action of silver nanoparticles and expand their use to fight infections, including tuberculosis.
Keywords:silver nanoparticles, tuberculosis, surgery, nanotechnology, induction of oxidative stress
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Citation link:
Tokaev T. K., Shtykhno A. O., Bikbaev A. S., Tokaev V. K., Sinitsyn M. V. THE USE OF SILVER NANOPARTICLES IN THE TREATMENT OF TUBERCULOSIS // Современная наука: актуальные проблемы теории и практики. Серия: Естественные и Технические Науки. -2024. -№11. -С. 260-266 DOI 10.37882/2223-2966.2024.11.36 |
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